George K Mutwiri : rechercher sur Z-Library

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Livres
Articles (73)
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1

Recent advances in experimental polyphosphazene adjuvants and their mechanisms of action

Magiri, Royford, Mutwiri, George, Wilson, Heather L.

Journal:

Cell and Tissue Research

Année:

2018

Langue:

english

Fichier:

PDF, 500 KB

english, 2018

2

Innate immune responses induced by CpG oligodeoxyribonucleotide stimulation of ovine blood mononuclear cells

Angelo Mena, Anil K. Nichani, Yurij Popowych, Dale L. Godson, Donna Dent, Hugh G. G. Townsend, George K. Mutwiri, Rolf Hecker, Lorne A. Babiuk, Philip Griebel

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 119 KB

english, 2003

3

PCEP enhances IgA mucosal immune responses in mice following different immunization routes with influenza virus antigens

Nelson F Eng, Srinivas Garlapati, Volker Gerdts, Lorne A Babiuk, George K Mutwiri

Journal:

Journal of Immune Based Therapies and Vaccines

Année:

2010

Langue:

english

Fichier:

PDF, 1.02 MB

english, 2010

4

Modulation of B cell responses by Toll-like receptors

Jayaum Booth, Heather Wilson, Steve Jimbo, George Mutwiri

Journal:

Cell and Tissue Research

Année:

2011

Langue:

english

Fichier:

PDF, 226 KB

english, 2011

5

Innate immunity: complex specificity

Philip Griebel, George Mutwiri, Baljit Singh

Journal:

Cell and Tissue Research

Année:

2011

Langue:

english

Fichier:

PDF, 90 KB

english, 2011

6

Approaches to enhancing immune responses stimulated by CpG oligodeoxynucleotides

George Mutwiri, Sylvia van Drunen Littel-van den Hurk, Lorne A. Babiuk

Journal:

Advanced Drug Delivery Reviews

Année:

2009

Langue:

english

Fichier:

PDF, 226 KB

english, 2009

7

CpG oligodeoxynucleotide induction of antiviral effector molecules in sheep

Anil K. Nichani, Radhey S. Kaushik, Angelo Mena, Yurij Popowych, Donna Dent, Hugh G.G. Townsend, George Mutwiri, Rolf Hecker, Lorne A. Babiuk, Philip J. Griebel

Journal:

Cellular Immunology

Année:

2004

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2004

8

B-cell activating factor (BAFF) promotes CpG ODN-induced B cell activation and proliferation

Rachelle M. Buchanan, Yurij Popowych, Natasha Arsic, Hugh G.G. Townsend, George K. Mutwiri, Andrew A. Potter, Lorne A. Babiuk, Philip J. Griebel, Heather L. Wilson

Journal:

Cellular Immunology

Année:

2011

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2011

9

Subcutaneous, but not intratracheal administration of the TLR9 agonist, CpG DNA transiently reduces parainfluenza-3 virus shedding in newborn lambs

Anil K. Nichani, M. Arshad Dar, Kuldip K. Mirakhur, Arthur M. Krieg, Jayaum S. Booth, Hugh G.G. Townsend, Andrew A. Potter, Lorne A. Babiuk, George K. Mutwiri

Journal:

Comparative Immunology, Microbiology and Infectious Diseases

Année:

2010

Langue:

english

Fichier:

PDF, 453 KB

english, 2010

10

Strategies for enhancing the immunostimulatory effects of CpG oligodeoxynucleotides

George K Mutwiri, Anil K Nichani, Shawn Babiuk, Lorne A Babiuk

Journal:

Journal of Controlled Release

Année:

2004

Langue:

english

Fichier:

PDF, 223 KB

english, 2004

11

Activation of adjuvant core response genes by the novel adjuvant PCEP

Sunita Awate, Heather L. Wilson, Ken Lai, Lorne A. Babiuk, George Mutwiri

Journal:

Molecular Immunology

Année:

2012

Langue:

english

Fichier:

PDF, 1.59 MB

english, 2012

12

Multiple intestinal ‘loops’ provide an in vivo model to analyse multiple mucosal immune responses

Volker Gerdts, Richard R.E. Uwiera, George K. Mutwiri, Don J. Wilson, Terry Bowersock, Argaw Kidane, Lorne A. Babiuk, Philip J. Griebel

Journal:

Journal of Immunological Methods

Année:

2001

Langue:

english

Fichier:

PDF, 586 KB

english, 2001

13

Oligodeoxynucleotides containing CpG motifs (CpG-ODN) predominantly induce Th1-type immune response in neonatal chicks

Bhavini A. Patel, Susantha Gomis, Arshud Dar, Philip J. Willson, Lorne A. Babiuk, Andrew Potter, George Mutwiri, Suresh K. Tikoo

Journal:

Developmental & Comparative Immunology

Année:

2008

Langue:

english

Fichier:

PDF, 539 KB

english, 2008

14

Co-stimulation with TLR7/8 and TLR9 agonists induce down-regulation of innate immune responses in sheep blood mononuclear and B cells

Jayaum S. Booth, Joram J. Buza, Andrew Potter, Lorne A. Babiuk, George K. Mutwiri

Journal:

Developmental & Comparative Immunology

Année:

2010

Langue:

english

Fichier:

PDF, 384 KB

english, 2010

15

Subcutaneous and intranasal immunization with type III secreted proteins can prevent colonization and shedding of Escherichia coli O157:H7 in mice

Shawn Babiuk, David J. Asper, Dragan Rogan, George K. Mutwiri, Andrew A. Potter

Journal:

Microbial Pathogenesis

Année:

2008

Langue:

english

Fichier:

PDF, 390 KB

english, 2008

16

Porcine TLR8 and TLR7 are both activated by a selective TLR7 ligand, imiquimod

Jianzhong Zhu, Ken Lai, Robert Brownile, Lorne A. Babiuk, George K. Mutwiri

Journal:

Molecular Immunology

Année:

2008

Langue:

english

Fichier:

PDF, 1.89 MB

english, 2008

17

Multiple molecular regions confer intracellular localization of bovine Toll-like receptor 8

Jianzhong Zhu, Sylvia van Drunen Littel-van den Hurk, Robert Brownlie, Lorne A. Babiuk, Andrew Potter, George K. Mutwiri

Journal:

Molecular Immunology

Année:

2009

Langue:

english

Fichier:

PDF, 1.95 MB

english, 2009

18

Characterization of bovine Toll-like receptor 8: Ligand specificity, signaling essential sites and dimerization

Jianzhong Zhu, Robert Brownlie, Qiang Liu, Lorne A. Babiuk, Andrew Potter, George K. Mutwiri

Journal:

Molecular Immunology

Année:

2009

Langue:

english

Fichier:

PDF, 2.04 MB

english, 2009

19

Chicken TLR21 acts as a functional homologue to mammalian TLR9 in the recognition of CpG oligodeoxynucleotides

Robert Brownlie, Jianzhong Zhu, Brenda Allan, George K. Mutwiri, Lorne A. Babiuk, Andrew Potter, Philip Griebel

Journal:

Molecular Immunology

Année:

2009

Langue:

english

Fichier:

PDF, 635 KB

english, 2009

20

All three classes of CpG ODNs up-regulate IP-10 gene in pigs

Arshud Dar, Anil Nichani, Ken Lai, Andy Potter, Volker Gerdts, Lorne A. Babiuk, George Mutwiri

Journal:

Research in Veterinary Science

Année:

2010

Langue:

english

Fichier:

PDF, 389 KB

english, 2010

21

Immunogenicity of a receptor-binding domain of SARS coronavirus spike protein in mice: Implications for a subunit vaccine

Alexander N. Zakhartchouk, Chetna Sharon, Malathy Satkunarajah, Thierry Auperin, Sathiyanarayanan Viswanathan, George Mutwiri, Martin Petric, Raymond H. See, Robert C. Brunham, B. Brett Finlay, Cheryl

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 310 KB

english, 2007

22

Poly[di(sodium carboxylatoethylphenoxy)phosphazene] (PCEP) is a potent enhancer of mixed Th1/Th2 immune responses in mice immunized with influenza virus antigens

George Mutwiri, Ponn Benjamin, Henry Soita, Hugh Townsend, Richard Yost, Bryan Roberts, Alexander K. Andrianov, Lorne A. Babiuk

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 621 KB

english, 2007

23

Co-administration of polyphosphazenes with CpG oligodeoxynucleotides strongly enhances immune responses in mice immunized with Hepatitis B virus surface antigen

George Mutwiri, Ponn Benjamin, Henry Soita, Lorne A. Babiuk

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 524 KB

english, 2008

24

Amended recombinant cells (ARCs™) expressing bovine IFN-γ: An economical and highly effective adjuvant system

Frank H. Gaertner, Lorne A. Babiuk, George Mutwiri, Janna M. Armstrong, Philip J. Griebel

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 691 KB

english, 2009

25

Efficacy of poly[di(sodium carboxylatophenoxy)phosphazene] (PCPP) as mucosal adjuvant to induce protective immunity against respiratory pathogens

Doo-Hee Shim, Hyun-Jeong Ko, Gerdts Volker, Andrew A. Potter, George Mutwiri, Lorne A. Babiuk, Mi-Na Kweon

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 876 KB

english, 2010

26

Immunogenicity and protective efficacy of an elastase-dependent live attenuated swine influenza virus vaccine administered intranasally in pigs

Aleksandar Masic, Xinya Lu, Junwei Li, George K. Mutwiri, Lorne A. Babiuk, Earl G. Brown, Yan Zhou

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2010

27

PCPP (poly[di(carboxylatophenoxy)-phosphazene]) microparticles co-encapsulating ovalbumin and CpG oligo-deoxynucleotides are potent enhancers of antigen specific Th1 immune responses in mice

Srinivas Garlapati, Nelson F. Eng, Heather L. Wilson, Rachelle Buchanan, George K. Mutwiri, Lorne A. Babiuk, Volker Gerdts

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 666 KB

english, 2010

28

Immunization with PCEP microparticles containing pertussis toxoid, CpG ODN and a synthetic innate defense regulator peptide induces protective immunity against pertussis

Srinivas Garlapati, Nelson F. Eng, Tadele G. Kiros, Jason Kindrachuk, George K. Mutwiri, Robert E.W. Hancock, Scott A. Halperin, Andrew A. Potter, Lorne A. Babiuk, Volker Gerdts

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 577 KB

english, 2011

29

Intradermal immunization using coated microneedles containing an immunoadjuvant

Alexander K. Andrianov, George Mutwiri

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 511 KB

english, 2012

30

The recombinant globular head domain of the measles virus hemagglutinin protein as a subunit vaccine against measles

Liubov M. Lobanova, Nelson F. Eng, Malathy Satkunarajah, George K. Mutwiri, James M. Rini, Alexander N. Zakhartchouk

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 434 KB

english, 2012

31

Bovine toll-like receptor 9: A comparative analysis of molecular structure, function and expression

Philip J. Griebel, Robert Brownlie, Anju Manuja, Anil Nichani, Neeloffer Mookherjee, Yurij Popowych, George Mutwiri, Rolf Hecker, Lorne A. Babiuk

Journal:

Veterinary Immunology and Immunopathology

Année:

2005

Langue:

english

Fichier:

PDF, 139 KB

english, 2005

32

Innate immune responses induced by classes of CpG oligodeoxynucleotides in ovine lymph node and blood mononuclear cells

Jayaum S. Booth, Anil K. Nichani, Ponn Benjamin, Arshud Dar, Arthur M. Krieg, Lorne A. Babiuk, George K. Mutwiri

Journal:

Veterinary Immunology and Immunopathology

Année:

2007

Langue:

english

Fichier:

PDF, 699 KB

english, 2007

33

Systemic innate immune responses following intrapulmonary delivery of CpG oligodeoxynucleotides in sheep

Anil K. Nichani, M. Arshud Dar, Arthur M. Krieg, Kuldip K. Mirakhur, Radhey S. Kaushik, Philip J. Griebel, Anju Manuja, Hugh G.G. Townsend, Lorne A. Babiuk, George K. Mutwiri

Journal:

Veterinary Immunology and Immunopathology

Année:

2007

Langue:

english

Fichier:

PDF, 728 KB

english, 2007

34

CD14+ cells are required for IL-12 response in bovine blood mononuclear cells activated with Toll-like receptor (TLR) 7 and TLR8 ligands

Joram Buza, Ponn Benjamin, Jianzhung Zhu, Heather L. Wilson, Grayson Lipford, Arthur M. Krieg, Lorne A. Babiuk, George K. Mutwiri

Journal:

Veterinary Immunology and Immunopathology

Année:

2008

Langue:

english

Fichier:

PDF, 747 KB

english, 2008

35

Attenuated cytokine responses in porcine lymph node cells stimulated with CpG DNA are associated with low frequency of IFNα-producing cells and TLR9 mRNA expression

Arshud Dar, Anil K. Nichani, Ponn Benjamin, Ken Lai, Henry Soita, Arthur M. Krieg, Andrew Potter, Lorne A. Babiuk, George K. Mutwiri

Journal:

Veterinary Immunology and Immunopathology

Année:

2008

Langue:

english

Fichier:

PDF, 737 KB

english, 2008

36

CD14+ cells are required for TLR7/8 ligand-induced IL-12 and IFN-γ responses in bovine blood mononuclear cells

Joram Buza, Ponn Benjamin, Jianzhung Zhu, Arthur M. Krieg, Lorne A. Babiuk, George K. Mutwiri

Journal:

Veterinary Immunology and Immunopathology

Année:

2009

Langue:

english

Fichier:

PDF, 84 KB

english, 2009

37

Strategies to link innate and adaptive immunity when designing vaccine adjuvants

Srinivas Garlapati, Marina Facci, Monika Polewicz, Stacy Strom, Lorne A. Babiuk, George Mutwiri, Robert E.W. Hancock, Melissa R. Elliott, Volker Gerdts

Journal:

Veterinary Immunology and Immunopathology

Année:

2009

Langue:

english

Fichier:

PDF, 534 KB

english, 2009

38

Interferon-gamma and B-cell Activating Factor (BAFF) promote bovine B cell activation independent of TLR9 and T-cell signaling

Rachelle Buchanan, Yurij Popowych, Crystal Dagenais, Natasa Arsic, George K. Mutwiri, Andrew A. Potter, Lorne A. Babiuk, Philip J. Griebel, Heather L. Wilson

Journal:

Veterinary Immunology and Immunopathology

Année:

2012

Langue:

english

Fichier:

PDF, 897 KB

english, 2012

39

Administration of poly[di(sodium carboxylatoethylphenoxy)]phosphazene (PCEP) as adjuvant activated mixed Th1/Th2 immune responses in pigs

Arshud Dar, Ken Lai, Donna Dent, Andrew Potter, Volker Gerdts, Lorne A. Babiuk, George K. Mutwiri

Journal:

Veterinary Immunology and Immunopathology

Année:

2012

Langue:

english

Fichier:

PDF, 351 KB

english, 2012

40

The immunogenicity and efficacy of replication-defective and replication-competent bovine adenovirus-3 expressing bovine herpesvirus-1 glycoprotein gD in cattle

P.Seshidhar Reddy, Neeraja Idamakanti, Caron Pyne, Alexander N Zakhartchouk, Dale L Godson, Zsuzsanna Papp, Maria E Baca-Estrada, Lorne A Babiuk, George K Mutwiri, Suresh K Tikoo

Journal:

Veterinary Immunology and Immunopathology

Année:

2000

Langue:

english

Fichier:

PDF, 167 KB

english, 2000

41

Response of calves to challenge exposure with virulent bovine respiratory syncytial virus following intranasal administration of vaccines formulated for parenteral administration

Ellis, John, Gow, Sheryl, West, Keith, Waldner, Cheryl, Rhodes, Carrie, Mutwiri, George, Rosenberg, Helene

Journal:

Journal of the American Veterinary Medical Association

Année:

2007

Langue:

english

Fichier:

PDF, 756 KB

english, 2007

42

Carrier molecules for use in veterinary vaccines

Gerdts, Volker, Mutwiri, George, Richards, James, Hurk, Sylvia van Drunen Littel-van den, Potter, Andrew A.

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 275 KB

english, 2013

43

TLR9 agonists: Immune mechanisms and therapeutic potential in domestic animals

Journal:

Veterinary Immunology and Immunopathology

Année:

2012

Langue:

english

Fichier:

PDF, 220 KB

english, 2012

44

Novel Bregs down-regulate TLR9-induced cytokine responses in sheep Peyer's patches

Jayaum Booth, Steve Jimbo, George Mutwiri

Journal:

Veterinary Immunology and Immunopathology

Année:

2012

Langue:

english

Fichier:

PDF, 183 KB

english, 2012

45

Microparticles for oral delivery of vaccines

Mutwiri, George, Bowersock, Terry L, Babiuk, Lorne A

Journal:

Expert Opinion on Drug Delivery

Année:

2005

Langue:

english

Fichier:

PDF, 329 KB

english, 2005

46

Immune Mechanisms and Therapeutic Potential of CpG Oligodeoxynucleotides

Wilson, Heather L., Dar, Arshud, Napper, Scott K., Marianela Lopez, A., Babiuk, Lorne A., Mutwiri, George K.

Journal:

International Reviews Of Immunology

Année:

2006

Langue:

english

Fichier:

PDF, 475 KB

english, 2006

47

CpG Oligodeoxynucleotides Activate Innate Immune Response that Suppresses Infectious Bronchitis Virus Replication in Chicken Embryos

Dar, Arshud, Potter, Andy, Tikoo, Suresh, Gerdts, Volker, Lai, Ken, Babiuk, Lorne A., Mutwiri, George

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 430 KB

english, 2009

48

Combination adjuvants: the next generation of adjuvants?

Mutwiri, George, Gerdts, Volker, van Drunen Littel-van den Hurk, Sylvia, Auray, Gael, Eng, Nelson, Garlapati, Srinivas, Babiuk, Lorne A, Potter, Andrew

Journal:

Expert Review of Vaccines

Année:

2011

Langue:

english

Fichier:

PDF, 502 KB

english, 2011

49

The adjuvant PCEP induces recruitment of myeloid and lymphoid cells at the injection site and draining lymph node

Awate, Sunita, Wilson, Heather L., Singh, Baljit, Babiuk, Lorne A., Mutwiri, George

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 1003 KB

english, 2014

50

CpG Oligodeoxynucleotides Activate Innate Immune Response That Suppresses Infectious Bronchitis Virus Replication in Chicken Embryos

Arshud Dar, Andy Potter, Suresh Tikoo, Volker Gerdts, Ken Lai, Lorne A. Babiuk and George Mutwiri

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 1.03 MB

english, 2009